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Salsalate Reduces Glycemia

Salsalate, a non-steroidal, anti-inflammatory medication which is similar to aspirin, is found to substantially reduce glycemia and lower inflammation, thereby reducing the risk of diabetes in obese young adults. Earlier studies connect inflammation in the development of type 2 diabetes and heart disease.

A study reported in Diabetes Care, found that people who took four grams per day of salsalate reduced their fasting glucose levels by 13 percent, and C-reactive protein concentrations (a marker of inflammation) was reduced by 34 percent.

Our study was the first to look at the metabolic changes that occur when you give salsalate to obese people who have not yet developed diabetes. And we’re really encouraged by what we found,” said Dr. Allison B. Goldfine, lead study researcher and assistant professor at Harvard Medical School and Research Investigator at the Joslin Diabetes Center.
The results of the study have prompted the National Institutes of Health to fund a larger, follow-up study on the safety and efficiency of salsalate in the treatment of type 2 diabetes. Studies are currently on¬going at multiple sites across the United States.

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