Generex Biotechnology Corporation, makers of the Generex Metformin Gum product, recently revealed results of a small study which showed that the gum presentation of metformin is as effective as the tablet form in the treatment of type 2 diabetes mellitus. Designed as a companion product to the company’s oral insulin spray product (Oral-lyn), Generex Metformin Gum is an alternative presentation of metformin that can be chewed, thereby delivering the active component metformin into the human cavity by the mouth.

Metformin is a drug used to treat type 2 diabetes in adults and children, especially when insulin resistance and obesity is present. The drug works by increasing the sensitivity of liver, muscle, fat and other tissues to the effects of insulin. Unlike other glucose-lowering drugs, metformin does not cause hypoglycemia (low blood sugar) and weight gain. Metformin users even report weight loss associated with metformin, suggesting an anorectic mechanism of the drug. However, a large number of metformin users develop gastrointestinal effects, including vomiting and nausea with the use of the drug.

The Generex Metformin Gum therefore shows promise as an alternative method of delivering metformin with lesser side effects. Manufacturers of metformin gum hope that the gum presentation can significantly avoid the significant adverse gastrointestinal effects associated with the tablet presentation of metformin, and that it may help improve patient compliance to their medication.

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