Prostate is a walnut-sized gland underneath the urinary bladder of males. An enlarged prostate (e.g. cancer) can place pressure at the urethra causing various urinary problems, especially among older men. In 2000, a study shows that diabetic men with Benign prostatic hyperplasia (BPH) have even greater urinary problems than non diabetic men with BPH. However, the growth of prostate cancer is so slow that most men will die before it becomes a problem. This is similarly true for both diabetic and non diabetic men.

Still, some studies claim that higher insulin levels among diabetics are associated with worse prognosis of prostate cancer. Thus, diabetics that are prone to have high insulin tend to be at risk of getting prostate cancer because accordingly prostate cancer cells are stimulated by insulin. These claims however are not yet validated and the association between diabetes and prostate remains minimal. In short, while the association of diabetes and prostate cancer is low in general, poorly managed diabetes can potentially contribute in causing prostate cancer.

On a lighter note, the Metformin drug used in the treatment of type 2 diabetes has shown positive signs that helps prevent prostate cancer. Although no conclusions have yet been attained, the Metformin drug especially acts on obese patients which in turn help prevent development of prostate cancer among diabetic patients.

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