All About Diabetes

Recent Austrian studies concluded that gastric stimulation could yield significant improvement in glycemic control among morbidly obese type 2 diabetes patients (ODM).

Bohdjalian et al (2009) recruited 24 ODM for a multicenter open-label European feasibility trial. Each of them were treated with insulin and/ or oral hyperglycemic agents and had a body mass index between 33.3 to 49.7 kg/m2. These participants were implanted laparoscopica ly with a TANTALUS system.

The TANTALUS system provided gastric electrical stimulation which is synchronized to the refractory period of gastric electrical activity. It was applied during meals and was evaluated for safety and for improvement of body weight and glucose control in obese type two diabetics.

Researchers from the Medical University of Vienna noted 18 adverse events related to the implant procedure or the device reported in 12 subjects. Accordingly, all were short-lived and resolved with no sequelae.

It was also noted in the large majority of subjects the significant reduction of weight by 4.5 +/- 2.7 kg (p < 0.05) and HbA1c by 0.5 +/- 0.3% (p < 0.05). Moreover, a subgroup (n = 11) on stable or reduced oral medication, registered a weight reduction by 6.3 +/- 3.4 kg (p < 0.05) and HbA1c by 0.9 +/- 0.4% (p < 0.05). The group on insulin (n = 6) had no significant changes in weight and HbA1c.

In conclusion, such findings prove the effectivity of the TANTALUS system among obese type 2 diabetic subjects. “Gastric electrical stimulation can potentially improve glucose metabolism and induce weight loss in obese diabetic patients, who are not well-controlled on oral antidiabetic therapy,” the researchers explained. “Further evaluation is required to determine whether this effect is due to induced weight loss and/or to direct signal dependent mechanisms.”

Do you regularly have headaches? Does your heart race? Are you irritable before meals? Do you feel confused or unable to make a decision? Are you constantly hungry? Are you always tired? Like Hollywood celebrities Burt Reynolds and Merv Griffin, you may be suffering from hypoglycemia, popularly known as “low blood sugar.” Read more… »

How can the elderly keep from having low blood sugars at night?

Hypoglycemia, defined variably as blood sugar <60 mg/dL, is one of the dreaded complications of diabetes management. It usually hinders the achievement of a satisfactory glucose control level because of the fear of developing symptoms of hypoglycemia – palpitations, excessive sweating, tremors, and disorientation. These “warning signs” are triggered by counter-regulatory hormones, like adrenalin, which are defense mechanisms of our body to increase sugar levels back to normal. Read more… »