Benefits of Candesartan
A treasure in the management of cardiometabolic diseases. In the last ten years, the prevalence of diabetes worldwide has increased at such an alarming rate, and the number of diabetics is expected to reach 350 million by 2025, which is barely 15 years from now. The Philippines is projected to be among the top ten countries showing a rapid increase in the prevalence of the disease. Diabetes has been known to cluster with other risk factors particularly hypertension—another killer—and local health experts are alarmed that diabetes and hypertension form a metabolic ‘time bomb’ waiting to explode, as it continues to maim or kill countless victims in the country and worldwide.
In a scientific symposium sponsored recently by LRI to launch their angiotensin receptor blocker Candez (candesartan cilexetil), three medical experts on diabetes and hypertension—Dr. Augusto D. Litonjua, Dr. Jorge Sison and Dr. Rafael R. Castillo—discussed the important role of a thorough global risk evaluation and treatment of patients diagnosed to have diabetes and hypertension; and how modulation of the renin angiotensin sytem (RAS) with an ARB such as candesartan can enhance vital-organ protection and improve clinical outcomes in terms of reduced macro-and microvascular complications in diabetics – even those who are not hypertensive.
Dr. Litonjua summed up his lecture and the whole scientific symposium with the following conclusions:
- The co-existence of multiple disorders in diabetes and hypertension make therapeutic priorities difficult.
- Diabetes, hypertension, obesity, and dyslipidemia require multi-drug treatment.
- Better implementation of therapies that reduce CV risk in diabetic patients will require moving beyond the traditional primary focus on glycemic control.
- Candesartan plays an important role in reducing CV risk in patients with hypertension and diabetes.
- A comprehensive approach and educational programs may be simultaneously beneficial.
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